Well it's as plausible Zananza broke his neck falling out of his chariot accidentally as it is a witness against the Mafia dies accidentally on the way to the Grand Jury.

Shall we agree on "highly suspicious" at least?

If Ankhesenamen would have viewed the Hittite Prince as uninvolved and loyal to her holding dynastic claims many others in the court, especially Horemheb, would look at him as a direct competitor.

Horemheb was beloved of the Army, there’s a lot of forts to pass on the journey...
Certainly rumors of Zanzara's imminent arrival would have given Horemheb dysentery of sorts.

Roxana wrote;
>” For all we know to the contrary Ankhes was conspiring against her grandfather's court party. Or she and Aye were conspiring together against Horemheb and his party. Or she
> Aye AND Horemheb were all partners against a conspiracy we know nothing about!”

These court intrigues are not just possible, they would likely run concurrently in the scramble for who got the prize.
The fact Ay married Ankhesenamen and shortly thereafter she disappeared from the record was likely the very event she feared enough to try an avoid by writing to Suppilulumia in the first place.

And yes, Roxana, I see why you love the tarpits.

Jammer